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PROTOCOL MAGNESIUM MATTERS

 

 

MAGNESIUM MATTERS         

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Magnesium is a critical mineral for a multitude of reasons

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Important Reading 
Read 'Magnesium Matters'. 
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Magnesium in heart and vascular health

A lack of magnesium creates shifts of calcium ions into the cells lining blood vessels (the Endothelium) which increases vascular tone and damages the lining. This vital mineral should never be forgotten in the treatment of hypertension and should be used as an adjunct in treating this condition. Blood pressure treatments may fail (refractory to treatment) because factors such as magnesium deficiency are forgotten in the management of disease states. 

Magnesium for Endometriosis

  • Inflammation drives endometriosis through many mechanisms4,5,6
  • Inflammation can itself drive pain and cause immune system cells to release inflammatory chemicals called Cytokines that can also drive pain
  • Inflammation helps endometrial cells spread 
  • The protocol on Endometriosis will list all the synergistic nutraceuticals that will help dampen inflammation 

Magnesium and insulin resistance 
 

Magnesium deficiency is linked to insulin resistance1,2. Insulin resistance in turn can lead to higher blood glucose levels and higher blood insulin and IgF-1 levels which can drive many cancers or rapidly multiplying cells or cell lines that spread such as Endometriosis. 

The higher the magnesium level, the lower the fasting blood insulin level was in a meta-analysis of 11 cohort studies1.

Magnesium lowers inflammation3

  • Inflammation drives heart
  • Inflammatrion drives cancers
  • Inflammation drives Alzheimer's and many chronic diseases
  • Inflammation drives Endometriosis 

 

Magnesium & Glutathione 

  • Gluththione is a vital antioxidant
  • Without glutathione and other antioxidants, your body will simply be a mass of inflammation due to oxidative stress 
  • Magnsesium is vital to the synthesis of glutathione
  • N-Acetylcysteine (NAC) is also vital to maintain glutathione levels

Magnesium is critical for energy production in cells

  • Cellular energy will only be created in the presence of magnesium
  • The enzyme that creates Adenosine Triphosphate (ATP) requires Magnesium to function
 

 


References: 

  1. Hruby A, Ngwa JS, Renstrom F, et al. Higher magnesium intake is associated with lower fasting glucose and insulin, with no evidence of interaction with select genetic loci, in a meta-analysis of 15 CHARGE Consortium Studies. J Nutr. 2013;143(3):345-353.
  2. Mooren FC, Kruger K, Volker K, Golf SW, Wadepuhl M, Kraus A. Oral magnesium supplementation reduces insulin resistance in non-diabetic subjects - a double-blind, placebo-controlled, randomized trial. Diabetes Obes Metab. 2011;13(3):281-284. 
  3. Mazur, A., et al. (2007). "Magnesium and the inflammatory response: potential physiopathological implications." Archives of Biochemistry and Biophysics 458(1): 48-56.
  4. Ziegler D, Borghese B et al. Endometriosis and infertility: pathophysiology and management. Lancet, 2010; 376: 730-738.
  5. Reis FM, Petraglia F, Taylor RN. Endometriosis: hormone regulation and clinical consequences of chemotaxis and apoptosis. Human reproduction update. Jul-Aug 2013;19(4):406-418.
  6. Capobianco, A., & Rovere Querini, P. (2013). Endometriosis, a disease of the macrophage. Frontiers in immunology, 4, 9.

 

 

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